Acute and Long-term post-vaccinal complications

A person of unidentified gender and age received the second dose of the mRNA vaccine BNT162b2 (Comirnaty®) against COVID-19. The patient experienced acute complications such as myocarditis and exacerbation of bronchial asthma, as well as long-term complications such as postural orthostatic tachycardia syndrome (POTS). The treatment for the patient included various medications, regimen measures, pharmacotherapy and several nutraceuticals. The pharmacotherapies included metoprolol, ivabradine, corticosteroids, antihistamines, antiphlogistics, and bronchodilators. The nutraceuticals used were maritime pine bark extract, quercetin, vitamins, magnesium, and phosphatidylcholine. 

There were no corresponding acute changes seen in the T1 and T2 maps, which are used to assess tissue characteristics. Handwritten note describes polymorphic patient complaints during 24-hour monitoring EKG (Department of Functional Diagnostics, UN - St. Michael's Hospital, a. s.; 29.9.2021)

The patient's condition stabilized and gradually improved with treatment. Five months later, the patient was able to do 5 squats or cycle on a stationary bike for a few minutes without significant symptoms. In an orthostatic test, the patient's tolerance interval for upright posture was prolonged from 2 to 7.5 minutes. 



REFERENCE

Varga I, Michalka P, Mištinová JP. Complications after administration of mRNA vaccine against COVID-19 - case report and short review. Vnitr Lek. 2023 Summer;69(E-4):20-27. English. doi: 10.36290/vnl.2023.054. PMID: 37468319.

Comments

Post a Comment

Popular posts from this blog

A New Onset of Ulcerative Colitis post-2nd-breakthrough-COVID-19

Image
A 21-year-old non-smoking Caucasian male with a history of acute pancreatitis but no other medical issues or family history had two doses of the BNT162b2 mRNA COVID-19 vaccine.  Four months after the second dose he had his first episode of COVID-19. Although not hypoxic, he felt pretty unwell for a week, with a severe cough, fever, generalized body ache, headache, and loss of taste. He received the third dose of the vaccine two months after recovering from COVID. Nine months after the third dose, he had the second episode of COVID-19, during which he was mildly unwell for three days, recovered, and did not require any anti-viral medication or antibiotics. One week post the second episode of COVID-19, he developed diarrhea and abdominal pain. It then progressed to bloody diarrhea. Ulcerative colitis was diagnosed based on his clinical symptoms, biopsy changes, and the exclusion of other causes.  There are ten published case reports about the newly diagnosed ulcerative colitis associate
Read more

COVID in May

Image
Concerns about a potential resurgence of COVID-19 are mounting as summer 2024 approaches.  This is driven by several indicators, including social media posts, healthcare data, and wastewater surveillance across different regions. Our study findings corroborate this trend.  While many forecasters anticipate a surge, others expect a gradual increase through the end of May, and then a decline again around early June. Reports from social media suggest emerging clusters of COVID-19 in Texas, several Canadian provinces, the UK, and on cruises in northern regions such as a Norwegian cruise to Alaska.  Data from Alberta's Respiratory virus dashboard   (total weekly laboratory-confirmed COVID-19 cases) and wastewater surveillance in Calgary indicate an uptick in COVID-19 cases starting April 2024. The most recent statistics from Alberta Health reveal a significant increase in hospitalizations due to COVID-19, with 114 individuals currently hospitalized—an increase of more than 20% over two
Read more

Chronic SARS-CoV-2 Shedding

Image
Chronic viral shedding, a condition where the virus continues to be released from an individual's body long after the initial infection, has been observed in many infectious diseases, including COVID-19.  In such cases, individuals may remain asymptomatic or experience only mild symptoms while the virus persists. It remains detectable in repeated tests over an extended period and can still infect others even in nasal swab is negative (which happens quite often ). This was evident in our study.    Recent research by Conway et al. (2024) highlights the possibility of chronic SARS-CoV-2 infection, extending over several months and potentially years. Other studies have documented prolonged asymptomatic infections and extended viral shedding in moderate to severe beyond hospital discharge. Analysis of sequencing data on UK samples taken between 2 November 2020 and 15 August 2022 lead to estimates that 0.1–0.5% of infections may become persistent with typically rebounding high viral load
Read more